PDRN injections are often mentioned alongside Rejuran when visitors research Korean skin boosters. This guide explains what PDRN is, what affects its cost in Korea, and which related options Dernia Clinic Myeongdong offers instead.
PDRN (polydeoxyribonucleotide) injections are DNA-fragment skin boosters used in Korea to support skin repair and calm stressed skin. Their cost depends on the product, the volume in cc, the area treated, the number of sessions and whether they are combined with microneedling. Dernia Clinic Myeongdong does not currently offer PDRN injections, so we do not quote a price for them. A closely related option we do offer is Rejuran Healer, a polynucleotide (PN) booster, from ₩259,000 for 2cc on the full face (KRW, excluding 10% VAT).
Prices are in Korean won, exclude 10% VAT and are confirmed by a doctor at consultation.
What is a PDRN skin injection?
PDRN stands for polydeoxyribonucleotide, a mixture of DNA fragments that are typically sourced from salmon. In Korea, PDRN has been used in medicine for wound-healing applications and is now widely used in aesthetic clinics as a skin booster. The idea is that these fragments support the skin's own repair processes, which may help with dullness, mild redness, fine texture issues and skin that feels thin or stressed.
PDRN is closely related to PN (polynucleotide), the ingredient in Rejuran. Both come from DNA, but PN chains are generally longer, which is thought to give PN a more lasting structural effect in the skin. In everyday Korean clinic language, the two are often discussed together, and some visitors use the terms interchangeably even though they refer to different product groups.
Does Dernia Clinic Myeongdong offer PDRN injections?
Dernia Clinic Myeongdong does not currently offer PDRN injections, and we do not quote a PDRN price. If you are interested in DNA-based skin repair, ask at your consultation about Rejuran Healer, a polynucleotide booster we do offer, or about exosome therapy as a supportive treatment. A doctor can explain whether either suits your goals.
We believe it is more useful to tell you plainly what we offer than to steer you toward a treatment that is not the right match. Many people who arrive asking about PDRN are really looking for calmer, stronger, more even skin, and there are several ways to work toward that.
What affects the cost of PDRN injections in Korea?
PDRN pricing in Korea varies between clinics, so it is more helpful to understand the factors behind a quote than to chase a single number. When you compare offers anywhere in Seoul, look at:
- Product and brand. There are several PDRN products in Korea, at different concentrations. Ask for the exact product name.
- Volume. Like most injectables, PDRN is priced by cc. A quote for a smaller volume may not cover the full face.
- Area. Face only, face and neck, or targeted areas such as under the eyes change the amount used.
- Delivery method. Manual injection, injector devices and microneedling-based delivery have different costs and different downtime.
- Number of sessions. PDRN is generally planned as a series, so the total cost is several sessions rather than one.
- VAT. Clinic prices in Korea are often quoted before 10% VAT. The tourist VAT refund on cosmetic procedures ended on January 1, 2026; see VAT refund changes in 2026.
PDRN vs Rejuran Healer: what is the difference?
| Point | PDRN injection | Rejuran Healer (PN) |
|---|---|---|
| Ingredient | Shorter DNA fragments (PDRN) | Longer polynucleotide chains (PN) |
| Main goals | Calming, repair support, glow | Repair, thickness, elasticity, calming |
| Typical course | Series of sessions | 3 sessions, 2–4 weeks apart |
| Downtime | Small bumps, mild redness | Small bumps for 1–3 days |
| At Dernia | Not currently offered | From ₩259,000 (2cc, full face) |
Neither product adds volume or lifts sagging skin. They are skin-quality treatments. If your main concern is sagging or hollows, your doctor will likely discuss lifting devices or volumizing options instead.
Rejuran Healer prices at Dernia (2026)
Because Rejuran Healer is the closest option we offer, here are its 2026 prices at Dernia Clinic Myeongdong:
| Plan | Typical coverage | Price (KRW) |
|---|---|---|
| 2cc | Full face, standard coverage | ₩259,000 |
| 3cc | Full face with extra on cheeks, pores or scars | ₩359,000 |
| 4cc | Full face and neck | ₩469,000 |
Prices exclude 10% VAT and are confirmed at consultation. See the Rejuran Healer price page. For the eye area, see Rejuran Eye.
Who is a good candidate for DNA-based skin boosters?
Usually a good fit
- Sensitive, easily irritated or redness-prone skin
- Thin or fragile-feeling skin
- Dull texture after sun exposure or stress
- Skin recovering from lasers or other procedures
Talk to the doctor first
- Fish or salmon allergy
- Pregnancy or breastfeeding
- Active infection, cold sores or inflamed acne in the area
- Autoimmune disease or a tendency to keloid scars
What happens at a skin booster appointment
- English consultation. A licensed doctor examines your skin, asks about allergies and medications, and explains which booster suits your goals. You agree the product, volume and price before anything starts.
- Cleansing and numbing. Numbing cream is applied for around 30 minutes, because booster injections use many small points across the face.
- Injection. The doctor places tiny amounts of product evenly across the treatment area, adjusting depth to your skin thickness.
- Soothing. A calming mask or cooling care settles redness before you leave, and you receive written aftercare in English.
The whole visit usually takes under an hour. Most people return to light sightseeing the same day, although small bumps are visible for a short time.
What results can you expect from DNA-based boosters?
Results from PN and PDRN boosters are gradual and subtle rather than dramatic. People commonly describe skin that feels calmer, more hydrated and more resilient, with a softer, more even look. Because the aim is to support the skin's own repair processes, changes typically build over the weeks after each session and are more noticeable after a full series than after a single visit.
Results vary with age, skin type, sun exposure and lifestyle. Taking photos in the same light before treatment and a few weeks after each session is the best way to judge your own response. See the Rejuran Healer results timeline for what is typical with PN.
Side effects and safety
DNA-based boosters are generally well tolerated when performed by a licensed doctor using genuine products. The most common effects are small raised bumps at each injection point, redness, mild swelling and occasional bruising. Injections can feel sharp, so numbing cream is usually applied first; read about Rejuran pain and numbing.
Rare risks include infection, prolonged swelling and allergic reactions. Because these products are derived from salmon, anyone with a fish allergy should raise this before treatment. If you notice increasing pain, heat or swelling after any injection, contact the clinic promptly.
Flying home? Bumps from DNA-based boosters usually settle within one to three days. If possible, leave a day or two before a long-haul flight. Our aftercare guide explains what to avoid afterward.
How to budget for skin repair treatments in Seoul
When you budget, think in terms of a full plan rather than a single session. Skin repair boosters usually work best in a series, then with maintenance. If you are only in Seoul for a few days, one session is still possible, but discuss realistic expectations with the doctor. Other ideas:
- Pair a booster with a gentle soothing session rather than an aggressive laser on the same trip.
- Ask whether the remaining sessions can be continued at home with your own doctor.
- Include VAT in your budget, since there is no tourist refund on cosmetic procedures in 2026.
Planning a skin booster around your Seoul trip
- Book ahead. Tell us your concerns and travel dates through our consultation form, and mention that you were interested in PDRN so the doctor can discuss alternatives.
- Avoid your arrival day. Schedule treatment for day two or later, after a night's rest.
- Getting here. Dernia is in Myeongdong, a short walk from Myeongdong Station (Line 4) and Euljiro 1-ga Station (Line 2).
- Leave buffer before flying. Give bumps time to settle before your flight home.
Frequently asked questions
How much does PDRN cost at Dernia Clinic Myeongdong?
Dernia does not currently offer PDRN injections, so there is no Dernia price. A related option, Rejuran Healer, starts from ₩259,000 for 2cc on the full face, excluding VAT.
Is PDRN the same as Rejuran?
Not exactly. Both are DNA-derived, but Rejuran contains polynucleotides (PN), which are longer chains than PDRN fragments.
How many PDRN sessions are usually needed?
PDRN is generally planned as a series of several sessions. The exact number depends on the product and your skin, and is set by the treating doctor.
Is PDRN safe if I have a fish allergy?
PDRN and PN are usually derived from salmon, so tell your doctor about any fish allergy before treatment. They may advise a different option.
What can I have instead of PDRN at Dernia?
Ask at consultation about Rejuran Healer, Rejuran Eye or exosome therapy. A doctor will recommend what fits your skin concerns and trip length.
Looking for skin repair treatment in Seoul?
Tell us your skin concerns and travel dates. A doctor will explain which repair-focused booster suits you and confirm the plan and price before any treatment.
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This article is for general information and does not replace a medical consultation. Results vary between individuals, and suitability, treatment plan and final price are confirmed by a licensed doctor after an in-person examination. Dernia Clinic Myeongdong does not publish patient testimonials or before-and-after claims.