Profhilo results timeline

Profhilo, made by IBSA, is a highly concentrated hyaluronic acid that combines high and low molecular weight HA in a thermally stabilized form. It is injected at a small number of set points on each side of the face and spreads through the skin by itself. Rather than adding shape, it hydrates and supports the skin, which becomes firmer and more elastic over a two-session course.

When	What you may notice	What is happening
Day 0	Five small raised bumps per side	HA is placed at set points
Day 1	Bumps have usually flattened	The product spreads evenly through the tissue
Weeks 1–2	Hydrated, dewy skin	HA holds water in the skin
Week 4	Second session	Builds on the first
Weeks 6–8	Firmer, bouncier skin and softer fine lines	The skin's supporting structure is improved
Month 6	Gradual fade	Time for a maintenance session

Read about how the treatment is performed on our Profhilo treatment page.

What improves and what doesn't

Usually improves

Dehydrated, dull skin
Crepey, thinning skin on the face and neck
Fine lines and mild loss of firmness
The look of the neck, hands and décolletage

Usually does not change

Marked volume loss or deep folds
Moderate to advanced sagging
Acne scars and pigmentation
Expression lines from muscle movement

Factors that influence your results

Completing both sessions: the second session is what turns hydration into firmer, more elastic skin.
Starting skin quality: thin, dry or crepey skin usually shows the clearest change.
Age: results are visible across ages, but mature skin may benefit from adding collagen-stimulating or lifting treatments.
Area: the neck and hands often need their own dose and schedule.
Lifestyle: sun exposure, smoking and dehydration shorten results.

How to maximize and maintain your results

Profhilo pairs well with treatments that work on other layers. If repair and texture matter, compare it with PN in Rejuran Healer vs Profhilo. If you mainly want glow, see Skinvive vs Profhilo. If loose skin is also a concern, many people pair a Profhilo course with radiofrequency or ultrasound lifting, usually scheduled on a separate day so each layer is treated cleanly and swelling from one does not mask the other.

Avoid makeup for about 12 hours and saunas or intense exercise for a day.
Don't massage the injection points.
Use a hydrating moisturizer and daily sunscreen.
Keep both sessions on schedule.

Realistic expectations and when to repeat

Profhilo gives better-quality skin, not a new shape. Most people see the clearest change a few weeks after the second session, and results typically last about six months. After that, one session every six months or so maintains them. Because the course needs two visits about four weeks apart, plan ahead; if you can't return in time, read what if you can't finish a treatment series. Our medical team's Profhilo review covers value, and pricing is on the Profhilo price page. Prices are in Korean won (KRW), exclude 10% VAT, and are confirmed at your consultation.

Tracking your progress

Hydration and firmness are subtle, so take photos before your first session, before your second, and about a month after the second.

Use the same window light and time of day, without flash.
Photograph bare skin with a neutral expression.
For the neck, keep your chin level and shoulders relaxed.
Take a slight smile photo to show fine lines around the eyes and mouth.

If your results aren't what you expected

Judge the result about a month after the second session. If you still see little change, contact Dernia and share your photos so your doctor can review them. They may suggest a different booster or a combination plan better suited to your skin. Explore other options in our results guides.

When will I see Profhilo results?

Skin usually looks more hydrated within one to two weeks of the first session. The clearer improvement in firmness appears a few weeks after the second session.

Do I need two Profhilo sessions?

The standard course is two sessions about four weeks apart. One session gives hydration, but the second builds firmness and elasticity.

How long does Profhilo last?

Results typically last about six months after the two-session course. Maintenance sessions about twice a year keep the benefit.

How long do Profhilo bumps last?

The small bumps at the injection points usually flatten within about 24 hours as the product spreads.

Can Profhilo be used on the neck?

Yes. The neck, hands and décolletage are common areas. Your doctor will advise the dose and schedule for each.

About the treatment

Profhilo in Seoul — high-concentration HA
Profhilo price — from ₩390,000 per session
Profhilo review — our medical team's verdict

Related boosters

Skinvive — microdroplet HA for glow
Rejuran Healer — PN for skin repair
Juvelook — collagen for texture

Concerns and guides

Dehydrated skin — treatment options
Neck lines and loose neck skin — what helps
Décolletage treatments — options for the chest
Skin boosters explained — PN, PDLLA, HA and exosomes

Dernia Clinic Myeongdong

Profhilo Results: Timeline and What to Expect